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Prof. Dr. Ali Avanoğlu
Vesicoureteral Reflux (VUR) • Treatment pathways

Ureteral Reimplantation (Anti-Reflux Surgery): Cohen, Lich-Gregoir

Ureteral reimplantation, used in vesicoureteral reflux (VUR), reconnects the ureter to the bladder through a new, longer tunnel. This operation, which has the highest success rate among reflux treatments, eliminates reflux with roughly 95–98% success in the literature. This page explains the principle behind the surgery, the techniques used, possible complications, and what to expect in hospital.

Who this is forFamilies whose child has been recommended ureteral reimplantation and who want to understand how the surgery is performed
Reading≈7 min
ByProf. Dr. Ali AvanoğluUpdated
This page is part of vesicoureteral reflux.Read the full treatment overview on the hub page
COHEN · through the bladder, cross-trigonal tunnelNew opening on the opposite side; the tunnel lengthensLICH-GREGOIR · from outside the bladderThe ureter is laid into a groove and covered with muscle
COHEN · through the bladder, cross-trigonal tunnelNew opening on the opposite side; the tunnel lengthensLICH-GREGOIR · from outside the bladderThe ureter is laid into a groove and covered with muscle
ureteral reimplantation: Cohen (through the bladder) and Lich-Gregoir (from outside)
In brief5 madde
  • The principle behind the surgery: lengthening the tunnel that acts as a valve: The ureter (the urine channel between the kidney and the bladder) does not enter the bladder at a right angle; it passes through an oblique tunnel within the bladder…
  • Intravesical approach: the Cohen cross-trigonal and Politano-Leadbetter techniques: In the Cohen technique, the bladder is opened, the ureter is freed from its own opening, and it is passed through a horizontal tunnel across the bladder base…
  • Extravesical approach: the Lich-Gregoir technique: In the Lich-Gregoir technique, the bladder is not opened.
  • Success and possible complications: Open ureteral reimplantation is one of the most predictable operations in pediatric urology: resolution of reflux is reported in the literature at roughly 95–98%.
  • Surgery day, hospital stay, and catheter: Surgery is performed under general anesthesia through a small horizontal incision in the lower abdomen, close to the bikini line; it takes roughly 1–1.5 hours for one…
01

The principle behind the surgery: lengthening the tunnel that acts as a valve

The ureter (the urine channel between the kidney and the bladder) does not enter the bladder at a right angle; it passes through an oblique tunnel within the bladder muscle before opening onto the inner surface. As the bladder fills and contracts, this tunnel is compressed from outside and works like a one-way valve. In vesicoureteral reflux, this tunnel is short, or the opening has shifted sideways; the valve fails to close and urine flows back up to the kidney.

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  • The aim of reimplantation is to rebuild this valve. The classic principle is that the tunnel length should be about five times the diameter of the ureter (a 5:1 ratio). The ureter is separated from the bladder wall, a new tunnel of sufficient length is prepared, and the ureter is passed through this tunnel and reconnected to the bladder. If the ureter is very wide (megaureter), its lower end may be narrowed to achieve the correct tunnel ratio.
  • This principle is shared by all techniques; they differ only in whether the tunnel is created from inside or outside the bladder, and where the ureter is repositioned.
02

Intravesical approach: the Cohen cross-trigonal and Politano-Leadbetter techniques

In the Cohen technique, the bladder is opened, the ureter is freed from its own opening, and it is passed through a horizontal tunnel across the bladder base (trigone) toward the opposite side, then stitched to its new opening. In bilateral reflux, the two ureters cross each other. Because the tunnel is horizontal, the risk of kinking and obstruction is low; this is the most widely used technique and the one with the most predictable results.

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  • In the Politano-Leadbetter technique, the ureter is again freed from inside the bladder, but a new entry point is created higher up on the bladder wall, and the ureter is brought down through a straight tunnel to a point near its original opening. This method provides a long tunnel and can be preferred especially for wide ureters; however, the risk of angulation and obstruction at the new entry point is somewhat higher than with Cohen.
  • Opening the bladder can cause bladder spasms and blood in the urine for a few days after surgery; these are expected, temporary effects. Because the ureter's new opening is in a crossed position with the Cohen technique, endoscopic access to the ureter in the future, if ever needed, is technically more difficult; this is a known detail that is factored in when planning the surgery.
03

Extravesical approach: the Lich-Gregoir technique

In the Lich-Gregoir technique, the bladder is not opened. At the point where the ureter enters the bladder, the bladder muscle is split lengthwise from the outside, the ureter is laid into this groove, and the muscle is closed back over it to create a new tunnel. Because the inner lining of the bladder is not disturbed, blood in the urine and bladder spasms are less common, catheter time is shorter, and the hospital stay is usually shorter too.

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  • This technique gives very good results in unilateral, moderate-to-high grade reflux where the ureter is not excessively wide. When performed bilaterally, involvement of the nerve fibers on the back-side surface of the bladder can cause temporary voiding difficulty (incomplete bladder emptying); this usually resolves within a few days to weeks, though a catheter or intermittent catheterization may be needed during that time. Nerve-sparing dissection, and performing the two sides in separate sessions when needed, reduces this risk.
  • Which technique is chosen depends on the side and grade of reflux, the diameter of the ureter, any accompanying anomaly, and the surgeon's experience; laparoscopic and robot-assisted reimplantation also mostly apply this extravesical principle using a minimally invasive approach.
04

Success and possible complications

Open ureteral reimplantation is one of the most predictable operations in pediatric urology: resolution of reflux is reported in the literature at roughly 95–98%. This figure depends less on the specific technique than on experience and correct patient selection.

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  • Possible complications are rare but should be understood. Obstruction in the new tunnel occurs in roughly 1–2% of cases; ultrasound follow-up is used to distinguish temporary swelling-related widening in the first weeks from a true, persistent narrowing. When only one side is operated on, new reflux appearing on the other side occurs in roughly 5–10% of cases; most are low grade and resolve on their own. Bleeding, wound infection, postoperative urinary tract infection, and persistent reflux are other rare possibilities.
  • Even when surgery is successful, infection risk is not brought to zero; if bladder-bowel dysfunction (BBD) continues, urinary tract infections can still recur. For this reason, monitoring bladder and bowel habits after surgery is considered part of the operation itself.
05

Surgery day, hospital stay, and catheter

Surgery is performed under general anesthesia through a small horizontal incision in the lower abdomen, close to the bikini line; it takes roughly 1–1.5 hours for one side, and somewhat longer for both sides. In our practice, reimplantation is carried out by the two pediatric urologists operating together; technical details are finalized through their joint assessment during surgery, based on the findings in the ureter and bladder.

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  • The hospital stay is usually 1–3 days; with intravesical techniques the urinary catheter stays in for a few days, while with the extravesical technique it stays in for a shorter time. If a wide ureter has been narrowed, or in high-grade bilateral repairs, a thin stent may be placed in the ureter; the stent is removed a few weeks later in a short procedure. Pain is controlled with regular oral pain relievers and, if needed, medication to reduce bladder spasms; the child is usually up and eating from the first day.
  • Follow-up ultrasound after surgery is done at 4–6 weeks and at around 12 months; if the ultrasound is normal and there is no febrile infection, a routine voiding cystourethrogram (VCUG) is not needed. home care and restrictions in the days after surgery is covered in a separate page.
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Frequently asked questions
Which is better — Cohen or Lich-Gregoir?
Both correct reflux with high success; which one is 'better' depends on the child. Cohen gives predictable results especially for bilateral cases and wide ureters; Lich-Gregoir provides an easier recovery in unilateral cases since the bladder is not opened. The decision is based on ureteral diameter, side, any anomaly, and experience.
Can reflux come back after surgery?
Rarely. In the literature, failure occurs in roughly 2–5% of cases, and most are noticed within the first year through a febrile infection or an ultrasound finding. New, low-grade reflux appearing on the other side is not a failure of the surgery — it is a known situation that usually resolves on its own.
How big is the scar?
It is a 4–6 cm horizontal scar in the lower abdomen, below the underwear line; it fades over time and becomes proportionally smaller as the child grows. With minimally invasive methods, a few small puncture scars remain instead; however, the choice of method is based on the characteristics of the reflux, not cosmetic considerations.
Does antibiotic prophylaxis continue after surgery?
It is usually continued until the follow-up ultrasound is seen to be normal — that is, for a few weeks to a few months — and then stopped. If a stent is in place, it is continued until the stent is removed. If a febrile infection occurs, a culture is taken and the plan is reassessed.
Does surgery improve kidney function?
Surgery does not reverse an existing scar; it protects the remaining kidney tissue by reducing the risk of new infection and new scarring. This is why, in children who already have scarring, yearly blood pressure, urine, and ultrasound follow-up continues after surgery as well.
Doç. Dr. Yaşar Issı's publications on this topic · 1
  1. Issi Y (2020). Non-Invasive Stent Removal after Ureteroneocystostomy in Pediatric Patients: Long-Term Results. Urology journal. PubMed ↗
Related pagesFull index →
Treatment pathwaysWhen Is Surgery Needed for Vesicoureteral Reflux?Most children diagnosed with vesicoureteral reflux (VUR) grow up without ever needing surgery. The decision to operate is not based on whether reflux is present, but on the harm it is causing — or could cause — to the kidney. This page explains when surgery for VUR comes up, when it doesn't, and how the decision is made.Treatment pathwaysLaparoscopic and Robot-Assisted ReimplantationIn addition to the open method, surgery for vesicoureteral reflux (VUR) can also be performed with a minimally invasive laparoscopic or robot-assisted (RALUR) approach. These methods, which offer small incisions and an easier recovery, have a success rate reported in the literature at roughly 88–97%, and one that depends markedly on the center's experience. This page explains what minimally invasive reimplantation is, who it suits, and how it compares with open surgery.After treatment and follow-upReimplantation Surgery Aftercare: Hospital Stay, Catheter, Home CareAfter vesicoureteral reflux surgery (ureteral reimplantation; re-implanting the ureter into the bladder), the child typically stays in the hospital for 1–3 days. The catheter, bladder spasms, and blood-tinged urine in the first days are what worry families most; this page explains step by step what to expect from the first day in the hospital through the return to school.After treatment and follow-upPossible Problems After Surgery: Obstruction, Persistent Reflux, Bladder SpasmUreteral reimplantation (vesicoureteral reflux surgery) is a highly reliable operation that corrects reflux in approximately 95–98% of cases in the literature. Even so, like any surgery, it has expected temporary findings and rare true problems. This page helps you tell which is which — which is normal and which needs further evaluation.
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