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Prof. Dr. Ali Avanoğlu
Vesicoureteral Reflux (VUR) • Bladder and bowel

Voiding Dysfunction, Urgency, Urinary Incontinence, and VUR

Daytime urinary incontinence, sudden urgency, and holding maneuvers are the most visible signs of voiding dysfunction in children. In a child with vesicoureteral reflux (VUR), these symptoms are not merely a social problem: high pressure and residual urine in the bladder feed infection and the persistence of reflux. This page explains the difference between 'urinary incontinence' and 'urine backflow (reflux)', and the treatment approach.

Who this is forFamilies of children with vesicoureteral reflux who have daytime urinary incontinence, urgency, or staccato voiding
Reading≈6 min
ByProf. Dr. Ali AvanoğluUpdated
This page is part of vesicoureteral reflux.Read the full treatment overview on the hub page
CONSTIPATION: a full bowel presses on the bladderBLADDERBOWEL (RECTUM)REGULAR EMPTYING: the bladder fills and empties easilyBLADDERBOWEL (RECTUM)
CONSTIPATION: a full bowel presses on the bladderBLADDERBOWEL (RECTUM)REGULAR EMPTYING: the bladder fills and empties easilyBLADDERBOWEL (RECTUM)
a full bowel presses on the bladder; with regular emptying the bladder fills easily
In brief4 madde
  • Urinary incontinence and vesicoureteral reflux are not the same thing: Families often confuse these two concepts.
  • Overactive bladder and holding maneuvers: Overactive bladder is the involuntary contraction of the bladder muscle before it is fully filled.
  • Dysfunctional voiding and residual urine: Dysfunctional voiding is the habitual contraction of the pelvic floor muscles and external urethral sphincter, which should relax during voiding.
  • When does reflux treatment come into consideration?: In a child with reflux who also has voiding dysfunction, the correct sequence is clear: bladder first, then reflux.
01

Urinary incontinence and vesicoureteral reflux are not the same thing

Families often confuse these two concepts. Urinary incontinence (or, at night, enuresis) is the involuntary leaking of urine out of the bladder into the underwear. Vesicoureteral reflux, on the other hand, is the backward flow of urine upward from the bladder into the kidney through the ureter (the urinary channel between the kidney and the bladder); it is not visible from the outside and does not cause wetness.

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  • Although these are different problems, they can occur together in the same bladder. A bladder that contracts at high pressure, does not empty fully, or contracts its outlet during voiding both wets the underwear and puts strain on the valve mechanism at the ureteral opening, sustaining the reflux. For this reason, voiding symptoms in a child with reflux are addressed with the same seriousness as the reflux itself.
  • Bedwetting alone (monosymptomatic enuresis), when not accompanied by daytime symptoms or infection, is not strongly related to reflux and follows a separate course. The pattern that matters for reflux is 'daytime-and-nighttime' incontinence, or daytime incontinence alone, where daytime symptoms are also present.
02

Overactive bladder and holding maneuvers

Overactive bladder is the involuntary contraction of the bladder muscle before it is fully filled. Its symptom is sudden, unpostponable urgency; the child voids frequently, sometimes doesn't make it in time, and leaks small amounts. This is the most common cause of daytime incontinence in children.

  • Crossing the legs, squatting, sitting on the heel
  • Suddenly freezing, bending forward, facial flushing
  • Leaking small amounts right after the urge to go
  • More than 8 voids a day, or constantly searching for a toilet
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  • The child develops holding maneuvers to suppress the contraction: crossing the legs, squatting and sitting on the heel, squeezing the penis, jumping on tiptoe, or bending forward and freezing. Families often mistake this for 'stalling'; in fact, it is a reflex contraction of the pelvic floor against the bladder's contraction, and it raises bladder pressure.
  • In a bladder that constantly operates at high pressure, the chance of reflux resolving on its own decreases, and infection recurrence increases. Treatment starts with standard urotherapy; if urgency and incontinence do not decrease sufficiently, an anticholinergic medication (oxybutynin and similar agents) is added. Because these medications can cause dry mouth and constipation, they are given together with bowel management, and residual urine is monitored.
03

Dysfunctional voiding and residual urine

Dysfunctional voiding is the habitual contraction of the pelvic floor muscles and external urethral sphincter, which should relax during voiding. Urine comes out in a staccato pattern or with pauses; the child strains, voiding takes longer, and the bladder does not empty completely.

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  • This picture generally develops from a long-standing holding habit and from constipation. Post-void residual urine is seen on ultrasound, a staccato curve on uroflowmetry, and contraction on the test that measures pelvic floor activity. Residual urine forms a 'pool' where bacteria multiply; in a child with reflux, the bacteria in this pool are directed toward the kidney with every void. High voiding pressure, in turn, is one of the factors that lowers the success rate of endoscopic injection.
  • The cornerstone of treatment is urotherapy and biofeedback, which teaches pelvic floor relaxation by displaying it on a screen. In selected cases, alpha-blocker medications that relax the bladder neck and ease emptying can be added (their use in children is confined to experienced centers and requires caution); however, medication does not replace behavioral treatment. Rarely, if symptoms are atypical or there is no response to treatment, underlying causes such as neurogenic bladder and posterior urethral valves (PUV) are investigated with urodynamics and imaging.
04

When does reflux treatment come into consideration?

In a child with reflux who also has voiding dysfunction, the correct sequence is clear: bladder first, then reflux. Once the bladder is calmed with urotherapy, constipation treatment, and medication if needed, infections stop in some children and reflux regresses on its own; no intervention is needed.

  • If incontinence begins together with fever, flank pain, or foul-smelling urine, get a urine culture the same day
  • New-onset daytime incontinence in a child who was previously dry
  • Continuous dribbling wetness (incontinence without interruption) — an anatomical cause is investigated
  • A weak, thin, or strained urine stream (especially in boys)
  • If reflux persists despite bladder improvement and febrile infections keep recurring, endoscopic injection or ureteral reimplantation (reconnecting the ureter to the bladder) is discussed; at this stage, the success of the procedure is markedly higher once performed on a bladder that has been corrected. In our practice, the follow-up of voiding dysfunction and the decision on reflux are carried out together by two pediatric urologists; bladder treatment is never decided in one place and the surgical decision in another.
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Frequently asked questions
My child only wets the bed at night; could this be reflux?
Bedwetting alone, without daytime symptoms or urinary tract infection, is generally not related to reflux and does not require an evaluation for reflux. However, if there is a history of febrile infection, or daytime urgency or incontinence, an evaluation is carried out.
Does medication for urinary incontinence also correct reflux?
Anticholinergic medication lowers pressure by reducing the bladder's involuntary contractions; this creates favorable conditions for reflux to resolve on its own and for infections to decrease, but it does not directly 'close' the reflux. Medication is always used together with urotherapy.
My child does holding maneuvers but doesn't leak; is this a problem?
Even without leaking, frequent holding maneuvers raise bladder pressure and increase the risk of infection and non-resolution in a child with reflux. Voiding by the clock, without waiting for the urge (timed voiding), breaks this cycle; the physician should be informed of it.
Does injection or surgery correct voiding dysfunction?
No; these procedures only repair the valve mechanism at the ureteral opening. If the bladder continues to operate at high pressure and without complete emptying, the risk of infection persists and the success rate of the procedure decreases. This is why voiding dysfunction is treated first.
Prof. Dr. Ali Avanoğlu and Doç. Dr. Yaşar Issı's publications on this topic · 4
  1. Tosun H, Issi Y, Akgul AK, et al. (2026). Is YouTube an Accurate and/or Comprehensive Source of Information on Monosymptomatic Nocturnal Enuresis? Journal of clinical practice and research. PubMed ↗
  2. Issi Y, Biçakci U (2021). Does desmopressin withdrawal strategy affect relapse rates in monosymptomatic enuresis treatment? European journal of pediatrics. PubMed ↗
  3. Ural Z, Ulman I, Avanoglu A (2008). Bladder dynamics and vesicoureteral reflux: factors associated with idiopathic lower urinary tract dysfunction in children. The Journal of urology. PubMed ↗
  4. Sözübir S, Ergun G, Celik A, et al. (2006). The influence of urine osmolality and other easily detected parameters on the response to desmopressin in the management of monosymptomatic nocturnal enuresis in children. Minerva urologica e nefrologica. PubMed ↗
Related pagesFull index →
Bladder and bowelWhat Is Bladder-Bowel Dysfunction (BBD), and How Does It Affect Reflux?Bladder-bowel dysfunction (BBD) is a condition in toilet-trained children in which voiding problems are intertwined with constipation. In children with vesicoureteral reflux (VUR), BBD both increases the recurrence of urinary tract infections and delays the resolution of reflux; for this reason, it is screened for and treated before deciding on reflux treatment.Bladder and bowelUrotherapy: Timed Voiding, Fluids, and Toilet HabitsUrotherapy is a drug-free, non-invasive education program that teaches the child to empty the bladder at the right time, in the right way, and completely. It is the first step of treatment in a child with vesicoureteral reflux (VUR) who also has voiding dysfunction or constipation, and it begins to show its effect within weeks.Bladder and bowelVoiding Diary, Uroflowmetry, and BiofeedbackThe voiding diary, uroflowmetry (urine flow measurement), and residual urine measurement are simple, painless, radiation-free tools that show how the bladder is working. They are used in a child with vesicoureteral reflux (VUR) to reveal voiding dysfunction and to monitor response to treatment; biofeedback, in turn, is the specific way of correcting the problem found.By age and special situationsSecondary VUR: Neurogenic Bladder and Posterior Urethral ValvesSecondary vesicoureteral reflux (VUR) arises not from a defect in the valve at the ureteral opening, but from high pressure in the bladder or from outlet obstruction. Neurogenic bladder and posterior urethral valves (PUV) are the two main examples, and here the order of treatment is reversed: the bladder and the valve come first, and the reflux most often regresses on its own.
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